The importance of genome-wide analysis of transcription factor families in plants
Regulated gene expression is one of the most complex activities in cells because it involves the integration of signal transduction pathways, the movement of proteins between cellular compartments, alterations in chromosome structure, RNA synthesis, and RNA processing. To understand plant growth and development at the molecular level, a detailed knowledge of the mechanisms of transcription is required.
Regulation of transcription can be controlled by the transcription factors (TFs) which bind the specific gene promoter sequences. Transcription factors (TFs) play an important role in growth and development of plants as well as all organisms in the nature. Up to date, approximately 30 TF families were identified and they were classified according to the conserved motifs that code for the DNA-binding domains. Approximately half of them were considered as plant specific TFs such as AP2/ERF, WRKY, NAC, B3, SBP and DOF families.
In recent genome – wide studies, bioinformatics approaches are being used for the identification of new proteins and genes in plants. Though omic technologies such as genomics, transcriptomics and metabolomics have become widespread, there is not enough study contains genome wide identification and expression analysis of transcription factor families in plant species such as common bean.
Dr. Sumer ARAS is currently a Professor at the Department of Biology, Faculty of Science at Ankara University in Ankara, Turkey. She graduated from Middle East Technical University (METU) with a bachelor’s degree in Biology in 1988. Dr. Aras earned a Masters degree in Molecular Biology from Cleveland State University in 1994 and she completed her PhD in 1998 at the Ankara University. Her research interests mainly focused on the investigation and exploration of response mechanisms in plant against abiotic stress conditions such as drought, salinity, heavy metal contamination etc.